Wallis Day will leave 'Hollyoaks'.
After a year on the show, bosses have cast Amanda Clapham in the role of Holly Cunningham to keep the character alive, after Day decided she wanted to leave the Channel 4 soap.
Clapham's first scenes will air in the next few weeks.
Wallis said in a statement: "I want to thank Lime Pictures for giving me such an incredible opportunity. I cannot express how grateful I've been for the last 18 months - I've learned so much and I hope to work with Lime again in the future.
"Congratulations to Amanda for being cast as Holly, I'm sure she'll do an excellent job working for such a great production company full of talented people."
Show bosses opted to recast the part ahead of some "major storylines" for Holly, but they are sad to see Wallis depart the programme.
A show spokesperson said: "A decision was made to recast the role ahead of some major storylines for the character which will take Holly in a different direction.
"Wallis Day has been a popular cast member and we wish her every success in her future."
Bryan Kirkwood, Hollyoaks' Executive Producer, added: "We're very sad to see Wallis go but respect her decision. I felt Holly is too good a character to lose, so we have recast the role and fans will see her later this autumn."
Wallis will still feature in episodes of 'Hollyoaks Later', which air nightly on E4 next week.