'Holby City' cast and crew members are filming the show for the final time today (17.12.21).
The BBC confirmed in June that the medical drama will come to a conclusion on screen in March after 23 years on air, and several stars have revealed the programme is shooting for the last ever time today.
David Ames, who portrays Dominic Copeland in the show, tweeted: "Right. Let’s do this. Final day here at @BBCHolbyCity.
Emotions are running high but we have pretend lives to save. (sic)"
'Casualty' star George Rainsford, who plays Ethan Hardy, who he has also portrayed in sister show 'Holby', praised the cast and crew as "amazing, talented people", as they prepared to clock off for the final time.
George tweeted: "To all my friends at @BBCHolbyCity, enjoy your last day. I can only imagine the emotions you’ll be feeling. You’re all such amazing, talented people. My time there has always been met with a wonderful sense of kindness & camaraderie. See you on the other side! #HolbyCity (sic)"
The BBC previously revealed 'Holby' was being axed to "make room for new opportunities".
In July, they said in a statement: "We are incredibly proud of 'Holby City' but it’s with great sadness that we are announcing that after 23 years, the show will end on screen in March of next year.
"We sometimes have to make difficult decisions to make room for new opportunities and as part of the BBC's commitment to make more programmes across the UK, we have taken the difficult decision to bring the show to a close in order to reshape the BBC's drama slate to better reflect, represent and serve all parts of the country.
"We would like to take this opportunity to thank the amazing team at BBC Studios and all the cast and crew who have been involved in the show since 1999.
"'Holby' has been a stalwart with audiences, delighting millions of viewers each week and winning hundreds of awards with a compelling mix of cutting-edge medical stories and explosive personal stories."
The corporation insisted they will make sure the programme - which features the likes of Jo Martin and former 'EastEnders' star Davood Ghadami - goes out "on a high".
They added: "We look forward to working with the team over the coming months to ensure that when it ends, Holby goes out on a high."
The show - which airs weekly on BBC One - launched on January 12, 1999, as a spin-off from fellow BBC medical drama 'Casualty', which began in September 1986.