The actress was said to have had the time of her life at the concert in New York on Tuesday after the soul superstar pulled her up onstage to serenade her.
The Gossip Girl star was one of the hitmaker's many celebrity fans in attendance at the Madison Square Garden show, but she got a special surprise when he plucked her out from the audience and brought her up onstage.
Meester couldn't contain her excitement as Prince and funk saxophonist Maceo Parker began to sing to her.
Blogging about the gig, The Roots drummer Ahmir '?uestlove' Thompson, who was also at the show, writes on his Twitte page, "Prince and Maceo are uh...sangin) to (ugh...the jawn (girl) from gossip girl who is not blonde). She's about to die onstage."
But the actress wasn't the only star to share the spotlight with Prince - comedian Jimmy Fallon was later invited to join the superstar's backing singers and add his vocals to a few songs.
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