The Hollywood actress was photographed in LA by David Sims.
The black and white ad campaign features Kate in a metallic trench coat and white jeans from the famous range. The shots are simple with Kate looking fresh-faced and stylish.
The label famously catapulted Kate Moss to supermodel status after she first starred in their adverts in 1992.
Kevin Carrigan, creative director of Calvin Klein Jeans said Kate Bosworth was perfect for the new campaign. "She is a true American beauty," he said: "Her purity of style and sensuality are a perfect match for the natural, clean modernity of the Calvin Klein Jeans line."
Kate, who starred in Superman Returns and is a regular on magazine fashion pages said: "To be featured in a Calvin Klein Jeans campaign, with its history of iconic imagery, is very exciting for me."
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