The actor and former model will be fronting their adverts for the next two seasons.
The campaign was photographed in New York by British fashion photographer David Sims, who has previously shots ads for Prada, Louis Vuitton and Yohji Yamamoto.
They will appear in the magazines GQ, Vogue, and Area Homme Plus in March.
Pepe jeans has recently undergone a restructure after UK sales manager Terry Peamen left.
Sienna Miller's clothing label Twenty8Tweleve, which she created with her sister Savannah was originally meant to be a capsual collection for the brand.
When it expanded she received backing from the Pepe Jeans owner Carlos Ortega..
Let's look forward to flicking through pages of hunky Ashton Kutcher adverts soon.
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