Renée Zellweger, Rob Lowe and Kristin Chenoweth have teamed up to front a new cancer awareness campaign.
The Hollywood stars have filmed and commercial for the Stand Up To Cancer organisations.
They hope to raise the profile of the disease and encourage the public to fight back against it.
Zellweger says, "It's up to me, it's up to you, it's up to all of us," while Lowe adds: "It's up to sons and daughters”
To advert shows stars writing slogans on a white wall, and will be shown in the U.S
Singers Alicia Keys and Justin Timberlake will also be involved with the campaign.
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