Chelsea Handler turned down Playboy for the sake of her family.
The comedienne and chat show host claims she rejected an offer to pose nude in the magazine because she was worried her brothers would be offended.
The 39-year-old star said: "I don't think any of my brothers need to see my vagina. I don't mind nudity, but I don't really need to have my vagina in a magazine."
The blonde beauty is close friends with a number of celebrities, including Jennifer Aniston, Reese Witherspoon and Charlize Theron, but insists most Hollywood stars aren't fascinating.
She told The Guardian newspaper: "I am sick of interviewing celebrities. Some are fascinating but most aren't."
Chelsea is stepping down from her show in August and wants to cover more serious topics, including politics.
She said: "A key component for having a television show is for you to be interested, because then your viewers are interested. The minute I'm not interested, it's not interesting to anyone who is watching.
"I don't want to focus solely on politics but it is definitely something I want to delve into. I don't want to be fluffy. I want people to be brave enough to sit there and answer any questions. There is nothing more annoying than people coming on your show and they don't want to talk about this or they don't want to talk about that. If you agree to do an interview you should be interviewed."
Tagged in Charlize Theron Jennifer Aniston Chelsea Handler