Bono would be "blind" if he hadn't been treated for glaucoma.
The U2 frontman has teamed up with Revo eyewear to launch a new range of sunglasses, with profits from every pair sold being donated to the Buy Vision, Give Sight campaign which, along with the company's partnership with the Brien Holden Vision Institute, is dedicated to preventing vision impairment and disease in over five million underserved people across the world by 2020.
And the 55-year-old singer admitted the cause is very close to home.
He said in a video announcing the collaboration: "I've been dealing with glaucoma for 20 years.
"I was told just yesterday that without the treatment I'm getting, I would be blind."
The campaign is aiming to earn $10 million in the next five years, and 10 dollars from every pair of Revo sunglasses sold - both from Bono's line and their other collections - will be donated to the cause.
The 'One' hitmaker previously revealed he wore his trademark sunglasses to ease some of the symptoms of the eye disease, which is a build-up of pressure in the eyeball which can damage the optic nerve and lead to blindness if left untreated.
He said: "This is a good place to explain to people that I've had glaucoma for the last 20 years. I have good treatments and I am going to be fine.
"You're not going to get this out of your head now and you will be saying, 'Ah, poor old blind Bono.'"