Lesbian and bisexual women have a higher risk of suffering from heart disease.
Researchers have recommended that cardiologists ask patients about their sexual orientation during heart checkups as lesbian and bisexual females are more likely to suffer from the disease than those who are straight.
However, gay men are at a lower risk compared to heterosexual males of the same age.
It is not clear why female minorities have a greater risk of heart disease but discrimination and higher poverty rates could be behind the findings.
The study suggested that knowing a patient's sexuality could "help improve" the healthcare that is offered.
Lead author Dr. Omar Deraz, of the Universite Paris Cite in France, said: "Improving cultural competency and awareness of cardiovascular disease risk among sexual minority adults may help to improve conversations between doctors and patients about cardiovascular health, including prevention and management.
"Understanding and overcoming barriers to health care access are essential to improve cardiovascular disease prevention and care in sexual minorities."